It’s a curious case of missing evidence. When a diabetes specialist searched the medical literature looking for proof to support the use of glucose-lowering drugs for Type 2 diabetes, he couldn’t find it.
That absence of evidence raises questions about one of the most firmly entrenched beliefs in modern medicine — that tightly controlling elevated blood sugar will reduce the risk of death, stroke, kidney failure, blindness and other dire outcomes associated with Type 2 diabetes.
“Does controlling your sugars reduce the risk of complications?” Dr. Victor Montori, of the Mayo Clinic in Rochester, Minn., asked in a paper released this month in the journal Circulation: Cardiovascular Quality and Outcomes. “Most experts say yes. The evidence appears to say ‘not so fast.'”